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The ingredient gap no one is talking about-until now

DAXXIFY® DREAM GETAWAY

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DAXXIFY® TREATMENT
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4-NIGHT STAY IN MIAMI OR LA
ENTER THE DREAM GETAWAY SWEEPSTAKES
DAXXIFY® TREATMENT
ROUND TRIP FLIGHT
4-NIGHT STAY IN MIAMI OR LA
ENTER THE DREAM GETAWAY SWEEPSTAKES
DAXXIFY® TREATMENT
ROUND TRIP FLIGHT
4-NIGHT STAY IN MIAMI OR LA
ENTER THE DREAM GETAWAY SWEEPSTAKES
DAXXIFY® TREATMENT

Do you know what’s in your frown line treatment?

A recent survey showed that Americans are more ingredient-aware than ever, but seem to have a blind spot when it comes to frown line treatments.

0%
said they're more ingredient-aware than ever before.
0%
said they would change to a different frown line treatment brand based on it's ingredients.
0%
believe that all frown line treatment formulas are “more or less the same” despite real differences in formulation.
*Based on a survey of 2,000 Americans aged 30-54.
One innovation changed the category:
a peptide formulation.

DAXXIFY® is the first and only frown line treatment with a peptide formulation — giving fast, lasting, natural-looking results.* Not only that, DAXXIFY® is the only frown line treatment made in the USA, and the only one free of human or animal-based ingredients.

See the difference of the peptide formulation.

The first innovation in neurotoxins in over 20 years, our unique formulation uses a peptide that forms a strong, magnet-like bond with the neuron, allowing more of the active ingredient to remain available over time. Watch the video to learn more about the only neurotoxin of its kind.

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*In clinical trial diaries, patients reported seeing a measurable improvement within 2 days. 74% of patients in clinical studies had improvement at week 4 per both physician's and patient's assessments. More than 50% had no or minor frown lines until 6 months after treatment per both physician's and patient's assessments. In an open label study (N=27), 96% of patients agreed their results looked natural (exploratory endpoint).

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DAXXIFY® DREAM GETAWAY SWEEPSTAKES

Enter for a chance to win an unforgettable getaway for you and a friend, plus a DAXXIFY® treatment.*

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*Treatment is for winning individual only. Official Rules apply.
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*Required.
NO PURCHASE NECESSARY. Void where prohibited. Open to legal residents of the 50 United States and D.C., who are at least 21 years old as of date of Entry. Begins 8:00 a.m. PT on September 15, 2025; ends 11:59 p.m. PT on December 31, 2025. For Official Rules and eligibility, visit daxxify.com/lp/dream-getaway-terms. Sponsor: Revance Therapeutics, Inc.
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See why everyone is talking about DAXXIFY®

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IMPORTANT SAFETY INFORMATION for DAXXIFY® (daxibotulinumtoxinA-Ianm) for injection
DAXXIFY® may cause serious side effects that can be life threatening. Get medical help right away if you have any of these problems any time (hours to weeks) after injection of DAXXIFY®: • Problems swallowing, speaking, or breathing due to weakening of associated muscles can be severe and result in loss of life. You are at the highest risk if these problems are pre-existing before injection.

IMPORTANT SAFETY INFORMATION for DAXXIFY® (daxibotulinumtoxinA-Ianm) for injection

DAXXIFY® may cause serious side effects that can be life threatening. Get medical help right away if you have any of these problems any time (hours to weeks) after injection of DAXXIFY®:

• Problems swallowing, speaking, or breathing due to weakening of associated muscles can be severe and result in loss of life. You are at the highest risk if these problems are pre-existing before injection. Swallowing problems may last for several months.

• Spread of toxin effects. The effect of botulinum toxin may affect areas away from the injection site and cause serious symptoms that include loss of strength and all-over muscle weakness, double vision, blurred vision and drooping eyelids, hoarseness or change or loss of voice, trouble saying words clearly, loss of bladder control, trouble breathing, and trouble swallowing.

Do not receive DAXXIFY® if you are allergic to any of the ingredients in DAXXIFY® (see Medication Guide for ingredients); had an allergic reaction to any other botulinum toxin product such as rimabotulinumtoxinB (MYOBLOC®), onabotulinumtoxinA (BOTOX®/BOTOX® Cosmetic), abobotulinumtoxinA (DYSPORT®), incobotulinumtoxinA (XEOMIN®) or prabotulinumtoxinA-xvfs (JEUVEAU®), or have a skin infection at the planned injection site.

DAXXIFY® dosing units are not the same as, or comparable to, any other botulinum toxin product.

Tell your healthcare provider about all your medical conditions, including any side effects from botulinum toxin products, including dry eye; breathing, swallowing, bleeding, or heart problems; plans to have surgery; weakness of forehead muscles; drooping eyelids; have had surgery on your face; are pregnant or breastfeeding or plan to become pregnant or breastfeed.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Using DAXXIFY® with certain other medicines may cause serious side effects. Do not start any new medicines until you have told your healthcare provider that you have received DAXXIFY® in the past.

Especially tell your healthcare provider if you have received any other botulinum toxin product in the last 4 months or any in the past, and exactly which product you received (such as BOTOX®, BOTOX® Cosmetic, MYOBLOC®, DYSPORT®, XEOMIN®, or JEUVEAU®). DAXXIFY® may cause serious side effects, including allergic reactions (such as itching, rash, redness, swelling, wheezing, trouble breathing, or dizziness or feeling faint), heart problems (such as irregular heartbeat and heart attack), and eye problems (including dry eye, reduced blinking, and corneal problems). Tell your healthcare provider or get medical help right away if you experience a serious side effect. No serious adverse events of distant spread of toxin effect associated with dermatologic use of DAXXIFY® have been reported in clinical studies at the dose of 40 Units for glabellar lines. The most common side effects of DAXXIFY® include headache, eyelid drooping, and loss of ability to move the muscles in your face.

These are not all the possible side effects of DAXXIFY®. For more information, see the full Prescribing Information including Boxed Warning, and refer to the Medication Guide or talk with your doctor. To report side effects associated with DAXXIFY®, please call 1-877-373-8669. You may also report side effects to the FDA at 1-800-FDA-1088 or visit www.fda.gov/medwatch.

APPROVED USE
DAXXIFY® is a prescription medicine that is injected into muscles and used in adults to temporarily improve the look of moderate to severe frown lines between the eyebrows.

DAXI-001723.2

©2025 REVANCE AESTHETICS. DAXXIFY, Revance Therapeutics and the Revance logo are registered trademarks of Revance Therapeutics, Inc. RHA is a registered trademark of TEOXANE SA. All other trademarks are the property of their respective owners.

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1222 Demonbreun Street, 20th floor
Nashville, TN 37203

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